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你正在浏览Journal of Toxicologic Pathology期刊下所有文献
  • A 90-day Feeding Toxicity Study of l-Serine in Male and Female Fischer 344 Rats.

    abstract：:A subchronic feeding study of l-serine (l-Ser) was conducted with groups of 10 male and 10 female Fischer 344 rats fed a powder diet containing 0, 0.06, 0.5, 1.5 or 5.0% concentrations of l-Ser for 90 days. There were no toxicologically significant, treatment-related changes with regards to body weight, food intake, w...

    journal_title：Journal of toxicologic pathology

    pub_type： 杂志文章

    doi：10.1293/tox.23.39

    authors： Tada Y,Yano N,Takahashi H,Yuzawa K,Ando H,Kubo Y,Nagasawa A,Chin K,Kawamata Y,Sakai R,Ohashi N,Ogata A,Nakae D

    更新日期：2010-03-01 00:00:00

  • No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats.

    abstract：:To clarify the modifying effect of N-Acetyl-L-Cysteine (NAC), which has antioxidative ability, on hepatocarcinogenesis promoted by fenofibrate (FF), a peroxisome proliferator-activated receptor (PPAR) alpha agonist , male F344/N rats were administered a single intraperitoneal injection of N-diethylnitrosamine (DEN) as...

    journal_title：Journal of toxicologic pathology

    pub_type： 杂志文章

    doi：10.1293/tox.22.255

    authors： Nishimura J,Dewa Y,Jin M,Saegusa Y,Kawai M,Kemmochi S,Shimamoto K,Harada T,Itoh T,Shima T,Shibutani M,Mitsumori K

    更新日期：2009-12-01 00:00:00

  • Distribution and sequence of pyknotic cells in rat fetuses exposed to busulfan.

    abstract：:Busulfan, an antineoplastic bifunctional-alkylating agent, is known to induce developmental anomalies. In the present study, we examined the distribution and sequence of pyknotic cells in rat fetal tissues exposed to busulfan. Pregnant rats on gestation day 13 were administered intraperitoneally 30 mg/kg of busulfan, ...

    journal_title：Journal of toxicologic pathology

    pub_type： 杂志文章

    doi：10.1293/tox.22.167

    authors： Ohira T,Ando R,Andoh R,Nakazawa T,Nishihara K,Yamamoto S,Nakamura N,Tamura K

    更新日期：2009-09-01 00:00:00

  • Spontaneous Cardiac Hypertrophy in a Crl:CD(SD) Rat.

    abstract：:Cardiac hypertrophy was observed in a 9-week-old Crl:CD(SD) rat that died unexpectedly. The animal was allocated to the control group of a toxicity study, and no abnormalities in its general conditions, body weight or food intake were observed. Necropsy revealed an increase in heart weight. Gross examination indicated...

    journal_title：Journal of toxicologic pathology

    pub_type： 杂志文章

    doi：10.1293/tox.22.83

    authors： Suzuki T,Kado S,Ando M,Nagata Y,Iwata S,Kobayashi T,Uchida K

    更新日期：2009-03-01 00:00:00

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